SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05018

Signal sequence   MFKKKMLAASLSVGLIAPLASPIQESRA

Length  28

Organism  Staphylococcus aureus

UniProt ID  O54081,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05018.cif

Structure  SPKB05018.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2958.61414

Aliphatic index  111.7857143

Isoelectric point  11.07952226

Charge (pH=7)   2.998871009

Topological polar surface area  1132.71

Aromaticity  0.035714286

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  41

X logP energy  -9.33753

Hydropathy 



Literature Information


Title  Characterization of a novel structural member, LukE-LukD, of the bi-component staphylococcal leucotoxins family.

DOI  10.1016/s0014-5793(98)01130-2,

Publication Year  1998

PubMed ID  9781679,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.