SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05011

Signal sequence   MKTLLLTLVLVTIMCLDLGYT

Length  21

Organism  Naja sputatrix (Malayan spitting cobra) (Naja naja sputatrix)

UniProt ID  O42257,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05011.cif

Structure  SPKB05011.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2354.99064

Aliphatic index  176.1904762

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  809.79

Aromaticity  0.047619048

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -2.0823

Hydropathy 



Literature Information


Title  Structurally conserved alpha-neurotoxin genes encode functionally diverse proteins in the venom of Naja sputatrix.

DOI  10.1016/s0014-5793(03)01039-1,

Publication Year  2003

PubMed ID  14572646,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.