SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05008

Signal sequence   MKKVIMALGVLAFANALMA

Length  19

Organism  Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)

UniProt ID  O25825,

Motif  1..19



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05008.cif

Structure  SPKB05008.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1992.57034

Aliphatic index  138.9473684

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  682.25

Aromaticity  0.052631579

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  26

X logP energy  -2.0126

Hydropathy 



Literature Information


Title  Purification and characterization of cytochrome c-553 from Helicobacter pylori.

DOI  10.1093/oxfordjournals.jbchem.a022763,

Publication Year  2000

PubMed ID  10965034,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.