SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05007

Signal sequence   MKSIISIAALSVLGLISKTMAAPAPAPVP

Length  29

Organism  Orpinomyces sp. (strain PC-2)

UniProt ID  O14412,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05007.cif

Structure  SPKB05007.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2848.53904

Aliphatic index  134.8275862

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  996.15

Aromaticity  0

Average rotatable bonds  3.034482759

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  39

X logP energy  -7.5028

Hydropathy 



Literature Information


Title  Sequencing of a 1,3-1,4-beta-D-glucanase (lichenase) from the anaerobic fungus Orpinomyces strain PC-2: properties of the enzyme expressed in Escherichia coli and evidence that the gene has a bacterial origin.

DOI  10.1128/jb.179.19.6028-6034.1997,

Publication Year  1997

PubMed ID  9324248,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.