SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05002

Signal sequence   MSGHILTVGLIVVVAHCATLSSS

Length  23

Organism  Phlebotomus papatasi (Sandfly)

UniProt ID  K9N4Q4,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05002.cif

Structure  SPKB05002.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2295.74064

Aliphatic index  143.9130435

Isoelectric point  7.523974965

Charge (pH=7)   0.117827765

Topological polar surface area  882.26

Aromaticity  0

Average rotatable bonds  3.173913043

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -9.4337

Hydropathy 



Literature Information


Title  Correction: Salivary Antigen SP32 Is the Immunodominant Target of the Antibody Response to Phlebotomus papatasi Bites in Humans.

DOI  10.1371/journal.pntd.0012303,

Publication Year  2024

PubMed ID  38959191,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.