SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05001

Signal sequence   MRLLTILALCCVAIWVVES

Length  19

Organism  Rat cytomegalovirus (isolate England) (RCMV-E) (Murid herpesvirus 8)

UniProt ID  K7XWG4,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05001.cif

Structure  SPKB05001.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2133.69674

Aliphatic index  179.4736842

Isoelectric point  6.135737489

Charge (pH=7)   -0.124193321

Topological polar surface area  742.57

Aromaticity  0.052631579

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  27

X logP energy  -1.75303

Hydropathy 



Literature Information


Title  Cytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+ CD4- dendritic cells.

DOI  10.1128/JVI.02330-13,

Publication Year  2014

PubMed ID  24155383,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.