SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05000

Signal sequence   MGRFIFLSSGWLVVFLSLSGTGA

Length  23

Organism  Bitis rhinoceros (West African gaboon viper) (Vipera rhinoceros)

UniProt ID  I7JUQ0,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05000.cif

Structure  SPKB05000.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2445.90484

Aliphatic index  114.3478261

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  882.36

Aromaticity  0.173913043

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  31

X logP energy  -6.02963

Hydropathy 



Literature Information


Title  Rhinocetin, a venom-derived integrin-specific antagonist inhibits collagen-induced platelet and endothelial cell functions.

DOI  10.1074/jbc.M112.381483,

Publication Year  2012

PubMed ID  22689571,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.