SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04990

Signal sequence   MKFAISTLLIILQAAAVFA

Length  19

Organism  Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1) (Yeast) (Pichia pastoris)

UniProt ID  F2QXM5,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04990.cif

Structure  SPKB04990.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2021.53214

Aliphatic index  164.7368421

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  696.69

Aromaticity  0.105263158

Average rotatable bonds  3.473684211

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -1.8371

Hydropathy 



Literature Information


Title  Crystal structure of linoleate 13R-manganese lipoxygenase in complex with an adhesion protein.

DOI  10.1194/jlr.M069617,

Publication Year  2016

PubMed ID  27313058,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.