SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04988

Signal sequence   MKFKKTIGAMALTTMFVAVSASA

Length  23

Organism  Escherichia coli O78:H11 (strain H10407 / ETEC)

UniProt ID  E3PPC4,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Fimbrium

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04988.cif

Structure  SPKB04988.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2404.97014

Aliphatic index  80.86956522

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  882.73

Aromaticity  0.086956522

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  35

X logP energy  -7.5423

Hydropathy 



Literature Information


Title  Purification and analysis of colonization factor antigen I, coli surface antigen 1, and coli surface antigen 3 fimbriae from enterotoxigenic Escherichia coli.

DOI  10.1128/jb.171.11.6372-6374.1989,

Publication Year  1989

PubMed ID  2572583,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.