SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04987

Signal sequence   MGRFTFVSFGLLVVFLSLSGTGA

Length  23

Organism  Protobothrops jerdonii (Jerdon's pitviper) (Trimeresurus jerdonii)

UniProt ID  E2DQZ6,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04987.cif

Structure  SPKB04987.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2406.86834

Aliphatic index  110

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  866.57

Aromaticity  0.173913043

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  31

X logP energy  -6.51253

Hydropathy 



Literature Information


Title  Jerdonuxin, a novel snaclec (snake C-type lectin) with platelet aggregation activity from Trimeresurus jerdonii venom.

DOI  10.1016/j.toxicon.2010.10.011,

Publication Year  2011

PubMed ID  21040740,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.