SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04986

Signal sequence   MVRFIFVSFGLLVVFLSLSGIGA

Length  23

Organism  Protobothrops jerdonii (Jerdon's pitviper) (Trimeresurus jerdonii)

UniProt ID  E2DQZ5,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04986.cif

Structure  SPKB04986.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2473.05764

Aliphatic index  156.5217391

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  826.11

Aromaticity  0.173913043

Average rotatable bonds  3.434782609

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -2.15733

Hydropathy 



Literature Information


Title  Jerdonuxin, a novel snaclec (snake C-type lectin) with platelet aggregation activity from Trimeresurus jerdonii venom.

DOI  10.1016/j.toxicon.2010.10.011,

Publication Year  2011

PubMed ID  21040740,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.