SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04974

Signal sequence   MSSGCLLLLLGLLTLWAELTPVSG

Length  24

Organism  Walterinnesia aegyptia (Desert black snake)

UniProt ID  C1IC52,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04974.cif

Structure  SPKB04974.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2488.03854

Aliphatic index  162.5

Isoelectric point  3.849962145

Charge (pH=7)   -1.062215294

Topological polar surface area  878.07

Aromaticity  0.041666667

Average rotatable bonds  3.291666667

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -4.9499

Hydropathy 



Literature Information


Title  Cloning, characterization and phylogenetic analyses of members of three major venom families from a single specimen of Walterinnesia aegyptia.

DOI  10.1016/j.toxicon.2008.02.012,

Publication Year  2008

PubMed ID  18405934,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.