SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04972

Signal sequence   MKSLQIICLLFIFVARGSC

Length  19

Organism  Elaphe climacophora (Japanese rat snake) (Coluber climacophorus)

UniProt ID  C0STK8,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04972.cif

Structure  SPKB04972.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2142.70704

Aliphatic index  143.6842105

Isoelectric point  8.828181491

Charge (pH=7)   1.873736522

Topological polar surface area  758.59

Aromaticity  0.105263158

Average rotatable bonds  3.789473684

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  28

X logP energy  -3.55093

Hydropathy 



Literature Information


Title  Identification and characterization of phospholipase A2 inhibitors from the serum of the Japanese rat snake, Elaphe climacophora.

DOI  10.1016/j.toxicon.2009.02.001,

Publication Year  2009

PubMed ID  19673083,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.