SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04971

Signal sequence   MKSSVPSLLFVSLVMSLNSYTQQ

Length  23

Organism  Elaphe climacophora (Japanese rat snake) (Coluber climacophorus)

UniProt ID  C0STK7,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04971.cif

Structure  SPKB04971.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2560.01874

Aliphatic index  105.6521739

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  1011.86

Aromaticity  0.086956522

Average rotatable bonds  3.652173913

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  38

X logP energy  -10.7103

Hydropathy 



Literature Information


Title  Identification and characterization of phospholipase A2 inhibitors from the serum of the Japanese rat snake, Elaphe climacophora.

DOI  10.1016/j.toxicon.2009.02.001,

Publication Year  2009

PubMed ID  19673083,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.