SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04965

Signal sequence   MKFLIVFVALFAMAVARP

Length  18

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  C0HL62,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04965.cif

Structure  SPKB04965.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2024.59974

Aliphatic index  135.5555556

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  637.15

Aromaticity  0.166666667

Average rotatable bonds  3.5

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  0.95857

Hydropathy 



Literature Information


Title  Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster.

DOI  10.1016/s0965-1748(97)00107-0,

Publication Year  1998

PubMed ID  9654737,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.