SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04961

Signal sequence   MKVAVVVALLCFVCYTAA

Length  18

Organism  Crassostrea virginica (Eastern oyster)

UniProt ID  B9A8D7,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04961.cif

Structure  SPKB04961.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1901.41424

Aliphatic index  146.1111111

Isoelectric point  8.221165971

Charge (pH=7)   0.872889419

Topological polar surface area  624.5

Aromaticity  0.111111111

Average rotatable bonds  3.222222222

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -1.5948

Hydropathy 



Literature Information


Title  Evidence indicating the existence of a novel family of serine protease inhibitors that may be involved in marine invertebrate immunity.

DOI  10.1016/j.fsi.2009.05.006,

Publication Year  2009

PubMed ID  19464375,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.