SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04954

Signal sequence   LANG

Length  4

Organism  Bothrops jararacussu (Jararacussu)

UniProt ID  B2D1Y0,

Motif  <1..4



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04954.cif

Structure  SPKB04954.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  373.40914

Aliphatic index  122.5

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  193.71

Aromaticity  0

Average rotatable bonds  2.75

Number of hydrogen bond donors  6

Number of hydrogen bond acceptors  6

X logP energy  -2.5745

Hydropathy 



Literature Information


Title  An alpha-type phospholipase A(2) inhibitor from Bothrops jararacussu snake plasma: structural and functional characterization.

DOI  10.1016/j.biochi.2008.05.009,

Publication Year  2008

PubMed ID  18549822,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.