SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04945

Signal sequence   MEAREVEEMRRSRLLTLG

Length  18

Organism  Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)

UniProt ID  A8ABZ0,

Motif  1..18



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04945.cif

Structure  SPKB04945.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2176.53724

Aliphatic index  86.66666667

Isoelectric point  6.669419424

Charge (pH=7)   0.005071545

Topological polar surface area  995.28

Aromaticity  0

Average rotatable bonds  4.333333333

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  31

X logP energy  -9.52292

Hydropathy 



Literature Information


Title  The dominating outer membrane protein of the hyperthermophilic Archaeum Ignicoccus hospitalis: a novel pore-forming complex.

DOI  10.1111/j.1365-2958.2006.05509.x,

Publication Year  2007

PubMed ID  17163971,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.