SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04940

Signal sequence   MVKMLFFAFLPLLFMTGIAA

Length  20

Organism  Chironex fleckeri (Australian box jellyfish)

UniProt ID  A7L035,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04940.cif

Structure  SPKB04940.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2261.91324

Aliphatic index  127

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  653.68

Aromaticity  0.2

Average rotatable bonds  3.55

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  26

X logP energy  2.4332

Hydropathy 



Literature Information


Title  Identification, cloning and sequencing of two major venom proteins from the box jellyfish, Chironex fleckeri.

DOI  10.1016/j.toxicon.2007.06.016,

Publication Year  2007

PubMed ID  17688901,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.