SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04927

Signal sequence   MASQVVLSFALVVVLAVFVGQVDS

Length  24

Organism  Ethmostigmus rubripes (Giant centipede)

UniProt ID  A0A023W140,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04927.cif

Structure  SPKB04927.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2478.97294

Aliphatic index  157.9166667

Isoelectric point  3.749987361

Charge (pH=7)   -1.001569216

Topological polar surface area  916.79

Aromaticity  0.083333333

Average rotatable bonds  3.291666667

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -6.1528

Hydropathy 



Literature Information


Title  Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts.

DOI  10.1016/j.jprot.2014.02.024,

Publication Year  2014

PubMed ID  24602922,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.