General Information
SPKB ID SPKB04926
Signal sequence MGRSISVSFGLLVVFLSLSGTGA
Length 23
Organism Macrovipera lebetinus (Levantine viper) (Vipera lebetina)
UniProt ID W5XDM0,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04926.cif
Physicochemical Information
Molecular weight 2298.72584
Aliphatic index 126.9565217
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 886.8
Aromaticity 0.086956522
Average rotatable bonds 3.260869565
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 32
X logP energy -9.34803
Hydropathy
Literature Information
Title Lebecin, a new C-type lectin like protein from Macrovipera lebetina venom with anti-tumor activity against the breast cancer cell line MDA-MB231.
DOI 10.1016/j.toxicon.2014.04.010,
Publication Year 2014
PubMed ID 24814013,
Patent ID NA,