General Information
SPKB ID SPKB04925
Signal sequence MGRIIFVSFGLLVVFLSLSGTGA
Length 23
Organism Macrovipera lebetinus (Levantine viper) (Vipera lebetina)
UniProt ID W5XCJ6,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04925.cif
Physicochemical Information
Molecular weight 2384.90544
Aliphatic index 143.9130435
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 846.34
Aromaticity 0.130434783
Average rotatable bonds 3.347826087
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 30
X logP energy -5.04383
Hydropathy 
Literature Information
Title Lebecin, a new C-type lectin like protein from Macrovipera lebetina venom with anti-tumor activity against the breast cancer cell line MDA-MB231.
DOI 10.1016/j.toxicon.2014.04.010,
Publication Year 2014
PubMed ID 24814013,
Patent ID NA,
