SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04911

Signal sequence   MKTVIFLIVSSLLLIGVKT

Length  19

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  Q9UAC9,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04911.cif

Structure  SPKB04911.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2075.66474

Aliphatic index  189.4736842

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  720.08

Aromaticity  0.052631579

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -1.9532

Hydropathy 



Literature Information


Title  Covalent structures of BmK AS and BmK AS-1, two novel bioactive polypeptides purified from Chinese scorpion Buthus martensi Karsch.

DOI  10.1016/s0041-0101(98)00190-1,

Publication Year  1999

PubMed ID  10080355,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.