General Information
SPKB ID SPKB04907
Signal sequence MMFRVTSVGCLLLVIVFLNLVVPTSA
Length 26
Organism Conus betulinus (Beech cone)
UniProt ID Q9U3Z3,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04907.cif
Physicochemical Information
Molecular weight 2823.54974
Aliphatic index 160.7692308
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 967.94
Aromaticity 0.076923077
Average rotatable bonds 3.423076923
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 36
X logP energy -4.30533
Hydropathy
Literature Information
Title A novel conotoxin from Conus betulinus, kappa-BtX, unique in cysteine pattern and in function as a specific BK channel modulator.
Publication Year 2003
PubMed ID 12547831,
Patent ID NA,