SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04906

Signal sequence   MKVIFVVLAIVLVTLWAMPSEA

Length  22

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  Q9TW32,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04906.cif

Structure  SPKB04906.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2431.07624

Aliphatic index  168.1818182

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  785.2

Aromaticity  0.090909091

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  0.4953

Hydropathy 



Literature Information


Title  The multigene immunophilin family of Dictyostelium discoideum. Characterization of microsomal and mitochondrial cyclophilin isoforms.

DOI  10.1016/s0300-9084(99)00225-4,

Publication Year  1999

PubMed ID  10575348,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.