SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04905

Signal sequence   MLRWFLSHLLGVWLLLSQLPREIPA

Length  25

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  Q9TRM8,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04905.cif

Structure  SPKB04905.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2989.66084

Aliphatic index  156

Isoelectric point  10.39953713

Charge (pH=7)   1.09066189

Topological polar surface area  1049.05

Aromaticity  0.12

Average rotatable bonds  3.72

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  34

X logP energy  -1.18086

Hydropathy 



Literature Information


Title  Purification and sequence determination of canine relaxin.

DOI  10.1007/BF01024863,

Publication Year  1992

PubMed ID  1388669,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.