SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04899

Signal sequence   MKIKTIIAVFGVLFSAHALA

Length  20

Organism  Methylophilus methylotrophus (Bacterium W3A1)

UniProt ID  Q9RQB9,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04899.cif

Structure  SPKB04899.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2130.66294

Aliphatic index  146.5

Isoelectric point  10.80542203

Charge (pH=7)   2.088303323

Topological polar surface area  737.4

Aromaticity  0.1

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -2.3016

Hydropathy 



Literature Information


Title  Cytochrome c" from the obligate methylotroph Methylophilus methylotrophus, an unexpected homolog of sphaeroides heme protein from the phototroph Rhodobacter sphaeroides.

DOI  10.1016/s0005-2728(99)00050-x,

Publication Year  1999

PubMed ID  10354493,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.