SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04897

Signal sequence   MKCFAQIVVLLLVIAFSHG

Length  19

Organism  Bombina variegata (Yellow-bellied toad)

UniProt ID  Q9PW66,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04897.cif

Structure  SPKB04897.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2089.62824

Aliphatic index  158.9473684

Isoelectric point  8.552755748

Charge (pH=7)   1.026623641

Topological polar surface area  705.14

Aromaticity  0.105263158

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -1.4847

Hydropathy 



Literature Information


Title  Bv8, a small protein from frog skin and its homologue from snake venom induce hyperalgesia in rats.

DOI  10.1016/s0014-2999(99)00229-0,

Publication Year  1999

PubMed ID  10422759,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.