SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04886

Signal sequence   MKWMVVAFICLQLLEA

Length  16

Organism  Callithrix jacchus (White-tufted-ear marmoset)

UniProt ID  Q9N2D3,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04886.cif

Structure  SPKB04886.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1895.40974

Aliphatic index  146.25

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  622.02

Aromaticity  0.125

Average rotatable bonds  3.875

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  0.8685

Hydropathy 



Literature Information


Title  New world monkey pepsinogens A and C, and prochymosins. Purification, characterization of enzymatic properties, cDNA cloning, and molecular evolution.

DOI  10.1093/oxfordjournals.jbchem.a022668,

Publication Year  2000

PubMed ID  10788784,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.