SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04884

Signal sequence   MGLWKSSPFLAFSILVLCQAGGLQA

Length  25

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  Q9MYV1,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04884.cif

Structure  SPKB04884.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2638.18094

Aliphatic index  117.2

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  941.61

Aromaticity  0.12

Average rotatable bonds  3.36

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -6.0446

Hydropathy 



Literature Information


Title  Elucidation of the sequence of canine (pro)-calcitonin. A molecular biological and protein chemical approach.

DOI  10.1016/0167-0115(91)90082-r,

Publication Year  1991

PubMed ID  1758974,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.