SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04877

Signal sequence   MSRIAKAAGVALGTGAVVLSGTGMAMA

Length  27

Organism  Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

UniProt ID  Q9KYH3,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04877.cif

Structure  SPKB04877.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2492.00834

Aliphatic index  101.4814815

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  988.76

Aromaticity  0

Average rotatable bonds  3.074074074

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -12.19653

Hydropathy 



Literature Information


Title  A novel class of secreted hydrophobic proteins is involved in aerial hyphae formation in Streptomyces coelicolor by forming amyloid-like fibrils.

DOI  10.1101/gad.264303,

Publication Year  2003

PubMed ID  12832396,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.