SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04876

Signal sequence   MGRFIFVSFGLLVVFLSLSGTAA

Length  23

Organism  Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)

UniProt ID  Q9IAM1,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04876.cif

Structure  SPKB04876.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2432.94954

Aliphatic index  131.3043478

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  846.34

Aromaticity  0.173913043

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -4.45873

Hydropathy 



Literature Information


Title  Purification, characterization, and cDNA cloning of a new fibrinogenlytic venom protein, Agkisacutacin, from Agkistrodon acutus venom.

DOI  10.1006/bbrc.1999.1685,

Publication Year  1999

PubMed ID  10558903,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.