SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04875

Signal sequence   MKSLQTICLLFIFIARGTS

Length  19

Organism  Malayopython reticulatus (Reticulate python) (Python reticulatus)

UniProt ID  Q9I8P7,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04875.cif

Structure  SPKB04875.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2142.64584

Aliphatic index  128.4210526

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  799.05

Aromaticity  0.105263158

Average rotatable bonds  3.789473684

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -5.37513

Hydropathy 



Literature Information


Title  Recombinant antitoxic and antiinflammatory factor from the nonvenomous snake Python reticulatus: phospholipase A2 inhibition and venom neutralizing potential.

DOI  10.1021/bi000395z,

Publication Year  2000

PubMed ID  10924158,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.