SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04869

Signal sequence   MMRHLLLVGAAILIFVSDAQA

Length  21

Organism  Lymnaea stagnalis (Great pond snail) (Helix stagnalis)

UniProt ID  Q9GU69,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04869.cif

Structure  SPKB04869.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2269.79184

Aliphatic index  158.0952381

Isoelectric point  7.550936504

Charge (pH=7)   0.089336563

Topological polar surface area  836.52

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -3.89563

Hydropathy 



Literature Information


Title  Neurotrophic actions of a novel molluscan epidermal growth factor.

DOI  10.1523/JNEUROSCI.20-17-06355.2000,

Publication Year  2000

PubMed ID  10964941,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.