SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04861

Signal sequence   MEAMKMKMMVFIMVVAVAFSAATA

Length  24

Organism  Arabidopsis thaliana (Mouse-ear cress)

UniProt ID  Q9C8A4,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04861.cif

Structure  SPKB04861.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2609.33364

Aliphatic index  89.58333333

Isoelectric point  9.537300927

Charge (pH=7)   0.999169354

Topological polar surface area  862.42

Aromaticity  0.083333333

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  36

X logP energy  -3.1619

Hydropathy 



Literature Information


Title  Post-translational modifications of arabinogalactan-peptides of Arabidopsis thaliana. Endoplasmic reticulum and glycosylphosphatidylinositol-anchor signal cleavage sites and hydroxylation of proline.

DOI  10.1074/jbc.M407594200,

Publication Year  2004

PubMed ID  15322080,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.