SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04850

Signal sequence   MKLVTIFLLVTISLCSYSATA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  Q96PL1,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04850.cif

Structure  SPKB04850.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2274.80244

Aliphatic index  148.5714286

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  812.95

Aromaticity  0.095238095

Average rotatable bonds  3.476190476

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -5.1551

Hydropathy 



Literature Information


Title  Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair.

DOI  10.4049/jimmunol.171.2.924,

Publication Year  2003

PubMed ID  12847263,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.