General Information
SPKB ID SPKB04844
Signal sequence MKIFFAILLILAVCSMAIWTVNG
Length 23
Organism Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)
UniProt ID Q95NK7,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04844.cif
Physicochemical Information
Molecular weight 2555.23614
Aliphatic index 156.9565217
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 828.88
Aromaticity 0.130434783
Average rotatable bonds 3.565217391
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -0.5874
Hydropathy
Literature Information
Title Purification and pharmacological characterization of BmKK2 (alpha-KTx 14.2), a novel potassium channel-blocking peptide, from the venom of Asian scorpion Buthus martensi Karsch.
DOI 10.1016/j.toxicon.2003.11.028,
Publication Year 2004
PubMed ID 15208022,
Patent ID NA,