General Information
SPKB ID SPKB04843
Signal sequence MKFIIVLILISVLIATIVPVNEA
Length 23
Organism Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)
UniProt ID Q95NJ8,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04843.cif
Physicochemical Information
Molecular weight 2510.20044
Aliphatic index 211.7391304
Isoelectric point 6.408795646
Charge (pH=7) -0.000535612
Topological polar surface area 841.6
Aromaticity 0.043478261
Average rotatable bonds 3.565217391
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 30
X logP energy -0.1131
Hydropathy
Literature Information
Title BmKK4, a novel toxin from the venom of Asian scorpion Buthus martensi Karsch, inhibits potassium currents in rat hippocampal neurons in vitro.
DOI 10.1016/s0041-0101(03)00136-3,
Publication Year 2003
PubMed ID 12906891,
Patent ID NA,