General Information
SPKB ID SPKB04842
Signal sequence MQALVLLLWTGALLGFGRCQ
Length 20
Organism Bos taurus (Bovine)
UniProt ID Q95121,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04842.cif
Physicochemical Information
Molecular weight 2190.69274
Aliphatic index 141.5
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 800.32
Aromaticity 0.1
Average rotatable bonds 3.55
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 27
X logP energy -3.69923
Hydropathy
Literature Information
Title Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop.
Publication Year 1995
PubMed ID 7592790,
Patent ID NA,