SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04841

Signal sequence   MKTLIFTLSSLQLIFLPQLSLG

Length  22

Organism  Tachypleus tridentatus (Japanese horseshoe crab)

UniProt ID  Q94823,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04841.cif

Structure  SPKB04841.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2464.04454

Aliphatic index  159.5454545

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  878.98

Aromaticity  0.090909091

Average rotatable bonds  3.727272727

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -4.2314

Hydropathy 



Literature Information


Title  Limulus intracellular coagulation inhibitor type 3. Purification, characterization, cDNA cloning, and tissue localization.

DOI  10.1074/jbc.271.39.23768,

Publication Year  1996

PubMed ID  8798603,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.