SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04829

Signal sequence   MNFGKAAIFGVVLFCLLWTEGAQA

Length  24

Organism  Aquarana catesbeiana (American bullfrog) (Rana catesbeiana)

UniProt ID  Q90W22,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04829.cif

Structure  SPKB04829.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2587.09254

Aliphatic index  105.8333333

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  918.14

Aromaticity  0.166666667

Average rotatable bonds  3.416666667

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -4.3306

Hydropathy 



Literature Information


Title  Bullfrog ghrelin is modified by n-octanoic acid at its third threonine residue.

DOI  10.1074/jbc.M105212200,

Publication Year  2001

PubMed ID  11546772,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.