SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04825

Signal sequence   MRTFWIVAMLLVGVEG

Length  16

Organism  Crotalus atrox (Western diamondback rattlesnake)

UniProt ID  Q8UVZ7,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04825.cif

Structure  SPKB04825.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1822.25694

Aliphatic index  133.75

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.125

Average rotatable bonds  3.625

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -0.95893

Hydropathy 



Literature Information


Title  Purification, sequencing, and phylogenetic analyses of novel Lys-49 phospholipases A(2) from the venoms of rattlesnakes and other pit vipers.

DOI  10.1006/abbi.2001.2524,

Publication Year  2001

PubMed ID  11594738,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.