SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04821

Signal sequence   MKRFAALSLAALMLLTVFASAASA

Length  24

Organism  Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)

UniProt ID  Q8TSG7,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04821.cif

Structure  SPKB04821.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2455.01494

Aliphatic index  126.6666667

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  901.46

Aromaticity  0.083333333

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -6.66403

Hydropathy 



Literature Information


Title  S-layer, surface-accessible, and concanavalin A binding proteins of Methanosarcina acetivorans and Methanosarcina mazei.

DOI  10.1021/pr800923e,

Publication Year  2009

PubMed ID  19228054,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.