SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04820

Signal sequence   MVFLKFFCMSFFCHLCQG

Length  18

Organism  Homo sapiens (Human)

UniProt ID  Q8TAL6,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04820.cif

Structure  SPKB04820.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2188.72724

Aliphatic index  59.44444444

Isoelectric point  8.06114472

Charge (pH=7)   0.902674209

Topological polar surface area  676.04

Aromaticity  0.277777778

Average rotatable bonds  3.833333333

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -1.1188

Hydropathy 



Literature Information


Title  Characterization of the expression, promoter activity and molecular architecture of fibin.

DOI  10.1186/1471-2091-12-26,

Publication Year  2011

PubMed ID  21615908,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.