SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04819

Signal sequence   MNFYKYLVVLVVLVLCLSATQTEA

Length  24

Organism  Stomoxys calcitrans (Stable fly) (Conops calcitrans)

UniProt ID  Q8T9R8,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04819.cif

Structure  SPKB04819.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2718.30534

Aliphatic index  150

Isoelectric point  6.225792706

Charge (pH=7)   -0.064211156

Topological polar surface area  983.27

Aromaticity  0.125

Average rotatable bonds  3.625

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -4.1902

Hydropathy 



Literature Information


Title  Epithelial innate immunity. A novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans.

DOI  10.1074/jbc.M206296200,

Publication Year  2002

PubMed ID  12372834,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.