SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04818

Signal sequence   MDSRICTSFARLMASALCVSTLLVTA

Length  26

Organism  Aplysia californica (California sea hare)

UniProt ID  Q8T0Y7,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04818.cif

Structure  SPKB04818.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2761.32374

Aliphatic index  112.6923077

Isoelectric point  8.231404231

Charge (pH=7)   0.874474729

Topological polar surface area  1093.53

Aromaticity  0.038461538

Average rotatable bonds  3.461538462

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  41

X logP energy  -12.13826

Hydropathy 



Literature Information


Title  Cloning, expression and processing of the CP2 neuropeptide precursor of Aplysia.

DOI  10.1016/s0196-9781(01)00561-7,

Publication Year  2001

PubMed ID  11786187,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.