SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04809

Signal sequence   MLTSAKILLISILSSLLLFGSHG

Length  23

Organism  Bos taurus (Bovine)

UniProt ID  Q8MI01,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04809.cif

Structure  SPKB04809.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2414.97234

Aliphatic index  173.9130435

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  879.6

Aromaticity  0.043478261

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -5.7595

Hydropathy 



Literature Information


Title  Isolation and characterization of MUC15, a novel cell membrane-associated mucin.

DOI  10.1046/j.1432-1033.2002.02949.x,

Publication Year  2002

PubMed ID  12047385,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.