SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04807

Signal sequence   MEMKNIFVALFISAVLVSSVSA

Length  22

Organism  Arabidopsis thaliana (Mouse-ear cress)

UniProt ID  Q8LD43,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04807.cif

Structure  SPKB04807.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2356.86424

Aliphatic index  137.2727273

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  861.75

Aromaticity  0.090909091

Average rotatable bonds  3.545454545

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -5.7228

Hydropathy 



Literature Information


Title  Post-translational modifications of arabinogalactan-peptides of Arabidopsis thaliana. Endoplasmic reticulum and glycosylphosphatidylinositol-anchor signal cleavage sites and hydroxylation of proline.

DOI  10.1074/jbc.M407594200,

Publication Year  2004

PubMed ID  15322080,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.