SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04806

Signal sequence   MSGSRLFFGVSTIVSIIFAILLPMAHA

Length  27

Organism  Arabidopsis thaliana (Mouse-ear cress)

UniProt ID  Q8L9T8,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04806.cif

Structure  SPKB04806.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2879.51464

Aliphatic index  133.7037037

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  1002.86

Aromaticity  0.111111111

Average rotatable bonds  3.37037037

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -5.72013

Hydropathy 



Literature Information


Title  Post-translational modifications of arabinogalactan-peptides of Arabidopsis thaliana. Endoplasmic reticulum and glycosylphosphatidylinositol-anchor signal cleavage sites and hydroxylation of proline.

DOI  10.1074/jbc.M407594200,

Publication Year  2004

PubMed ID  15322080,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.