SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04797

Signal sequence   MAFRMKLVVCIVLLSTLAVMSSA

Length  23

Organism  Acanthoscurria gomesiana (Tarantula spider) (Phormictopus pheopygus)

UniProt ID  Q8I948,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04797.cif

Structure  SPKB04797.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2484.17354

Aliphatic index  148.2608696

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  872.36

Aromaticity  0.043478261

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -4.84013

Hydropathy 



Literature Information


Title  Acanthoscurrin: a novel glycine-rich antimicrobial peptide constitutively expressed in the hemocytes of the spider Acanthoscurria gomesiana.

DOI  10.1016/s0145-305x(03)00058-2,

Publication Year  2003

PubMed ID  12818635,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.